10 Photos

$400,000

450 Main Street

n/a, Cape Girardeau, Missouri, 63701

MLS® 26008598 · Listed by EDGE Realty ERA Powered

0 bedroomsCommercial Sale1 day on marketBuilt 1920Lot 32670.00$3,221 taxes (2025)None

About this property

Location and visibility set this property apart. This prime riverfront commercial asset offers over the perfect location for downtown development and parking, making it well suited for a wide range of uses. Situated directly along the Mississippi River, the property presents exceptional potential for office, restaurant, warehouse, or mixed-use concepts and has a warehouse currently on the property. Opportunities like this are rare so don’t miss the chance to secure a highly versatile riverfront commercial property.

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MLS® data for this listing last updated Mar 12, 2026.

Market snapshot

The n/a, Cape Girardeau market

Closed sales in n/a, Cape Girardeau over the last 12 months.

$399,900

Median sold price

63

Avg. days on market

31

Homes sold

Median sold price by month

Median sold price trend from Sep 2025 ($609,500) to Jul 2026 ($144,500)Sep 2025Jul 2026